Interações medicamentosas
Magnesium + Roxadustat
Gravidade: Moderada
Magnesium and Roxadustat: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Magnesium-containing products can bind roxadustat in the gut and reduce how much is absorbed. Lower exposure may blunt the haemoglobin response to treatment.
O que esta interação significa em palavras simples
Magnesium and Roxadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Magnesium belongs to Gastrointestinal Tract; Roxadustat belongs to Miscellaneous.
Por que acontece
Chelation of roxadustat by multivalent cations in the gastrointestinal tract reduces its absorption.
O que fazer
Give roxadustat at least 1 hour after magnesium-containing products. Monitor haemoglobin and adjust roxadustat dose if the response is inadequate.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Roxadustat
- Gemfibrozil + Roxadustat Grave
- Probenecid + Roxadustat Grave
- Atorvastatin + Roxadustat Moderada
- Calcium acetate + Roxadustat Moderada
- Calcium + Roxadustat Moderada
- Iron + Roxadustat Moderada
Outras interações de Magnesium
- Ciprofloxacin + Magnesium Grave
- Magnesium + Pancuronium Grave
- Magnesium + Rocuronium Grave
- Magnesium + Vecuronium Grave
- Amikacin + Magnesium Moderada
- Amphotericin b deoxycholate + Magnesium Moderada
Perguntas frequentes
Can I take Magnesium with Roxadustat?
MediHelp rates the interaction as moderate. Magnesium and Roxadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium-containing products can bind roxadustat in the gut and reduce how much is absorbed. Lower exposure may blunt the haemoglobin response to treatment.
How serious is the interaction between Magnesium and Roxadustat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give roxadustat at least 1 hour after magnesium-containing products. Monitor haemoglobin and adjust roxadustat dose if the response is inadequate.
What other medicines interact with Roxadustat?
MediHelp also lists interactions of Roxadustat with, for example, Gemfibrozil, Probenecid, Atorvastatin. The full list is on the Roxadustat page.
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