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藥品參考

Clodronate

Clodronate is a medicine in the class musculoskeletal. It is used for hypercalcemia of malignancy.

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Musculoskeletal
常見劑型
注射劑
常見規格
60 mg/ml, 400 mg
商品名
2
國家與市場
1

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Bisphosphonate; binds to hydroxyapatite crystals in bone and inhibits osteoclast-mediated bone resorption; decreases mineral release and collagen or matrix breakdown in bone

成人常用劑量(仿單摘要)

Oral: The recommended daily dose is 2 tablets (1600mg sodium clodronate) taken as a single dose. Not recommended to exceed 3200 mg daily.

僅摘錄仿單中第一行劑量說明;完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Unsafe Bisphosphonate: binds to bone, and animal data show it crosses the placenta; it could affect fetal bone and calcium. Human data are limited. Not recommended in pregnancy or in women not using effective contraception.
哺乳
Unknown Not known if it passes into milk; little would be absorbed by the infant. The label says a risk cannot be excluded and to stop breastfeeding during treatment.

已通報的副作用

  • Vomiting
  • Diarrhea
  • Nausea
  • Bronchospasm
  • Hypocalcaemia
  • Increased AST

哪些人需要特別留意

  • While on treatment, these patients should avoid invasive dental procedures if possible.
  • During bisphosphonate treatment patients should be advised to report any thigh, hip or groin pain and any patient presenting with such symptoms should be evaluated.

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可開啟 Clodronate 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Paediatric dosing
  • Dosing in older adults
  • Patient counselling points
  • Food interactions

在網頁版免費試用 Pro+ 14 天,無需信用卡。

同類別的其他藥品

常見問題

What is Clodronate used for?

Clodronate is a medicine in the class musculoskeletal. It is used for Hypercalcemia of malignancy, Osteolytic bone lesions of MM, Osteolytic bone metastases of BC.

What side effects have been reported with Clodronate?

Vomiting, Diarrhea, Nausea, Bronchospasm, Hypocalcaemia, Increased AST.

Can Clodronate be taken in pregnancy or while breastfeeding?

Pregnancy: Unsafe. Bisphosphonate: binds to bone, and animal data show it crosses the placenta; it could affect fetal bone and calcium. Human data are limited. Not recommended in pregnancy or in women not using effective contraception. Breastfeeding: Unknown. Not known if it passes into milk; little would be absorbed by the infant. The label says a risk cannot be excluded and to stop breastfeeding during treatment.

What does Clodronate interact with?

MediHelp does not list a checked interaction for Clodronate yet. Always tell your pharmacist about every medicine you take.

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在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。

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