藥品參考
Flutamide
Flutamide is a medicine in the class endocrine. It is used for prostate cancer.
- 藥物類別: Endocrine
- 用途: prostate cancer
最後更新
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Endocrine
- 常見劑型
- 錠劑, 膠囊
- 常見規格
- 250 mg, 125 mg
- 已知交互作用
- 32 (嚴重: 5 · 中度: 18 · 輕微: 9)
- 商品名
- 4
- 國家與市場
- 3
用途
作用方式
Nonsteroidal antiandrogen, competitively binds androgen receptors and inhibits testosterone stimulation of cell growth in prostate cancer
成人常用劑量（仿單摘要）
250 mg PO q8hr Take in combination with gonadotropin-releasing hormone (GnRH/LHRH) analogs
懷孕與哺乳
- 懷孕
- Unsafe Anti-androgen for prostate cancer; not for use in pregnancy. In animals it feminised male fetuses and lowered offspring survival. If used off-label in women (e.g. hirsutism), exclude pregnancy and use effective contraception.
- 哺乳
- Unknown Not indicated for women; no data on passage into milk. Anti-androgen effects on a male infant and liver toxicity are possible, so avoid while breastfeeding.
已通報的副作用
- Vomiting
- Diarrhea
- Nausea
- Impotence
- Hot flashes
- Decreased libido
哪些人需要特別留意
- Risk of severe liver injury
- Potential for aniline toxicity (methemoglobinemia, hemolytic anemia etc); specially monitor patients sensitive to aniline toxicity
- Risk for cardiovascular disease may increase with androgen deprivation
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (32)
- Flutamide + Idelalisib Major
- Flutamide + Levoketoconazole Major
- Flutamide + Pexidartinib Major
- Flutamide + Pretomanid Major
- Flutamide + Valoctocogene roxaparvovec Major
- Apalutamide + Flutamide Moderate
- Bupivacaine implant + Flutamide Moderate
- Cannabidiol + Flutamide Moderate
- Cobicistat + Flutamide Moderate
- Danazol + Flutamide Moderate
同類別的其他藥品
常見問題
What is Flutamide used for?
Flutamide is a medicine in the class endocrine. It is used for Prostate cancer.
What side effects have been reported with Flutamide?
Vomiting, Diarrhea, Nausea, Impotence, Hot flashes, Decreased libido.
Can Flutamide be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Anti-androgen for prostate cancer; not for use in pregnancy. In animals it feminised male fetuses and lowered offspring survival. If used off-label in women (e.g. hirsutism), exclude pregnancy and use effective contraception. Breastfeeding: Unknown. Not indicated for women; no data on passage into milk. Anti-androgen effects on a male infant and liver toxicity are possible, so avoid while breastfeeding.
What does Flutamide interact with?
MediHelp lists 32 known interactions for Flutamide. Major: 5 · Moderate: 18 · Minor: 9. The most serious include Idelalisib, Levoketoconazole, Pexidartinib.
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