藥品參考
Fluvastatin
Fluvastatin is a medicine in the class cardiovascular. It is used for dyslipidemia.
- 藥物類別: Cardiovascular
- 用途: dyslipidemia
最後更新
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重點資訊
- 藥物類別
- Cardiovascular
- 常見劑型
- 錠劑, 膠囊
- 常見規格
- 80 mg, 40 mg
- 已知交互作用
- 126 (嚴重: 5 · 中度: 52 · 輕微: 69)
- 商品名
- 8
- 國家與市場
- 5
用途
作用方式
HMG-CoA reductase inhibitor, inhibits the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase
成人常用劑量（仿單摘要）
Hypercholesterolemia & Mixed Dyslipidemia: Start 20-40 mg PO qHS, Dose range 20-80 mg PO qDay
一般服用方式
Statins are taken by mouth once a day, long term, with blood tests to check the response and liver function.
懷孕與哺乳
- 懷孕
- Unsafe EU/UK labels and the old-format US capsule label contraindicate it in pregnancy (reduced fetal cholesterol synthesis); the current US ER label (2023) says stop when pregnancy is recognised unless the need is compelling. Statin data show no rise in birth defects. Stop before or when pregnant.
- 哺乳
- Unsafe No human milk data; it passes into rat milk (milk-to-plasma ratio 2:1). US label: contraindicated while breastfeeding because of possible effects on infant lipid metabolism. LactMed: avoid; an alternative is preferred.
已通報的副作用
- Headache
- Fatigue
- Diarrhea
- Insomnia
- Abdominal pain
- Dyspepsia
哪些人需要特別留意
- Lipid-lowering effects additive with bile-acid binding resin or niacin
- Rare reports of immune-mediated necrotizing myopathy (IMNM), characterized by increased serum creatine kinase that persist despite discontinuing statin
- Heavy alcohol use, history of liver disease, renal failure
Unexplained muscle pain, tenderness or weakness while taking a statin should be reported promptly. Statins are not used in pregnancy, and some other medicines raise their levels and risk.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (126)
- Cyclosporin + Fluvastatin Major
- Cyclosporine + Fluvastatin Major
- Fluvastatin + Gemfibrozil Major
- Fluvastatin + Letermovir Major
- Fluvastatin + Red yeast rice Major
- Apalutamide + Fluvastatin Moderate
- Cholestyramine + Fluvastatin Moderate
- Colchicine + Fluvastatin Moderate
- Colestipol + Fluvastatin Moderate
- Danicopan + Fluvastatin Moderate
同類別的其他藥品
常見問題
What is Fluvastatin used for?
Fluvastatin is a medicine in the class cardiovascular. It is used for Dyslipidemia, Hypercholesterolemia.
What side effects have been reported with Fluvastatin?
Headache, Fatigue, Diarrhea, Insomnia, Abdominal pain, Dyspepsia.
Can Fluvastatin be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. EU/UK labels and the old-format US capsule label contraindicate it in pregnancy (reduced fetal cholesterol synthesis); the current US ER label (2023) says stop when pregnancy is recognised unless the need is compelling. Statin data show no rise in birth defects. Stop before or when pregnant. Breastfeeding: Unsafe. No human milk data; it passes into rat milk (milk-to-plasma ratio 2:1). US label: contraindicated while breastfeeding because of possible effects on infant lipid metabolism. LactMed: avoid; an alternative is preferred.
What does Fluvastatin interact with?
MediHelp lists 126 known interactions for Fluvastatin. Major: 5 · Moderate: 52 · Minor: 69. The most serious include Cyclosporin, Cyclosporine, Gemfibrozil.
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