藥物交互作用
Fluvastatin + Red yeast rice
嚴重程度: 嚴重
Fluvastatin and Red yeast rice: major interaction.
最後更新
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摘要
Red yeast rice contains monacolin K, which is chemically identical to lovastatin. Combined with fluvastatin it duplicates HMG-CoA reductase inhibition and increases the risk of myopathy and liver injury.
用白話說明這項交互作用的意義
Fluvastatin and Red yeast rice can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Fluvastatin belongs to Cardiovascular; Red yeast rice belongs to Gastrointestinal Tract.
為什麼會發生
Duplicate HMG-CoA reductase inhibition
處置方式
Do not combine; stop the supplement and record it in the medication history, and monitor CK and liver enzymes if there are symptoms.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Fluvastatin 的其他交互作用
Red yeast rice 的其他交互作用
常見問題
Can I take Fluvastatin with Red yeast rice?
MediHelp rates the interaction as major. Fluvastatin and Red yeast rice can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Red yeast rice contains monacolin K, which is chemically identical to lovastatin. Combined with fluvastatin it duplicates HMG-CoA reductase inhibition and increases the risk of myopathy and liver injury.
How serious is the interaction between Fluvastatin and Red yeast rice?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; stop the supplement and record it in the medication history, and monitor CK and liver enzymes if there are symptoms.
What other medicines interact with Fluvastatin?
MediHelp also lists interactions of Fluvastatin with, for example, Cyclosporine, Cyclosporin, Gemfibrozil. The full list is on the Fluvastatin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
