藥物交互作用
Danicopan + Fluvastatin
嚴重程度: 中度
Danicopan and Fluvastatin: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Danicopan inhibits BCRP and raises exposure to BCRP substrates. Fluvastatin is partly handled by BCRP, so its concentrations may increase and raise the risk of muscle toxicity.
用白話說明這項交互作用的意義
Danicopan and Fluvastatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Danicopan belongs to Miscellaneous; Fluvastatin belongs to Cardiovascular.
為什麼會發生
Danicopan inhibits BCRP, reducing fluvastatin efflux and increasing exposure.
處置方式
Monitor for myopathy and consider limiting the fluvastatin dose. Check creatine kinase if muscle symptoms appear.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Fluvastatin 的其他交互作用
Danicopan 的其他交互作用
常見問題
Can I take Danicopan with Fluvastatin?
MediHelp rates the interaction as moderate. Danicopan and Fluvastatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Danicopan inhibits BCRP and raises exposure to BCRP substrates. Fluvastatin is partly handled by BCRP, so its concentrations may increase and raise the risk of muscle toxicity.
How serious is the interaction between Danicopan and Fluvastatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for myopathy and consider limiting the fluvastatin dose. Check creatine kinase if muscle symptoms appear.
What other medicines interact with Fluvastatin?
MediHelp also lists interactions of Fluvastatin with, for example, Cyclosporine, Cyclosporin, Gemfibrozil. The full list is on the Fluvastatin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
