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藥品參考

Atogepant

Atogepant is a medicine in the class central nervous system. It is used for migraine.

最後更新 來源: US FDA label, EMA SmPC

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Central Nervous System
ATC 代碼
N02CD07
常見劑型
錠劑
已知交互作用
110 (中度: 43 · 輕微: 67)
商品名
2
國家與市場
2

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Atogepant is a calcitonin gene-related peptide (CGRP) receptor antagonist.

成人常用劑量(仿單摘要)

Episodic migraine prevention: 10 mg, 30 mg, or 60 mg orally once daily, with or without food

僅摘錄仿單中第一行劑量說明;完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Unknown Limited human data. Animal studies showed lower fetal weight and skeletal variations above human exposures. UK/EU labels: not recommended in pregnancy; a migraine treatment with more data is preferred.
哺乳
Unknown Passes into milk in low amounts; no data on infant effects or milk supply. Weigh breastfeeding benefits against the mother's need; watch the infant.

已通報的副作用

  • Nausea
  • Constipation
  • Fatigue/somnolence
  • Decreased appetite
  • Dizziness

禁忌症

  • History of hypersensitivity to atogepant or any component of QULIPTA (reactions have included anaphylaxis and dyspnea).

哪些人需要特別留意

  • Hypersensitivity reactions including anaphylaxis can occur, even days after administration; discontinue and treat if they occur.
  • New-onset or worsening hypertension reported postmarketing; monitor blood pressure and consider discontinuation if not otherwise explained or uncontrolled.
  • Raynaud's phenomenon may develop or worsen; discontinue if signs or symptoms develop.

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。

重要交互作用 (110)

All 110 interactions, with severity and what to do

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解鎖完整頁面

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  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • Dosing in older adults
  • How to give it
  • Pharmacokinetics
  • Patient counselling points
  • Food interactions

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同類別的其他藥品

常見問題

What is Atogepant used for?

Atogepant is a medicine in the class central nervous system. It is used for Migraine.

What side effects have been reported with Atogepant?

Nausea, Constipation, Fatigue/somnolence, Decreased appetite, Dizziness.

Can Atogepant be taken in pregnancy or while breastfeeding?

Pregnancy: Unknown. Limited human data. Animal studies showed lower fetal weight and skeletal variations above human exposures. UK/EU labels: not recommended in pregnancy; a migraine treatment with more data is preferred. Breastfeeding: Unknown. Passes into milk in low amounts; no data on infant effects or milk supply. Weigh breastfeeding benefits against the mother's need; watch the infant.

What does Atogepant interact with?

MediHelp lists 110 known interactions for Atogepant. Moderate: 43 · Minor: 67. The most serious include Amobarbital, Apalutamide, Aprepitant.

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