藥品參考
Luspatercept
Luspatercept is a medicine in the class miscellaneous. It is used for anemia.
- 藥物類別: Miscellaneous
- 用途: anemia
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Miscellaneous
- ATC 代碼
- B03XA06
- 常見劑型
- 注射劑
- 常見規格
- 25 mg
- 商品名
- 3
- 國家與市場
- 3
用途
作用方式
Recombinant fusion protein that binds several endogenous TGF-β superfamily ligands, diminishing Smad2/3 signaling and promoting erythroid maturation, thereby increasing erythropoiesis.
成人常用劑量（仿單摘要）
Beta thalassemia anemia requiring regular RBC transfusions: start 1 mg/kg subcutaneously once every 3 weeks; increase to 1.25 mg/kg if no reduction in RBC transfusion burden; maximum 1.25 mg/kg
懷孕與哺乳
- 懷孕
- Unsafe May cause fetal harm: in rats and rabbits it caused fetal death, poor growth and malformations. No human data. Do not use in pregnancy; women who could become pregnant need a pregnancy test before starting and effective contraception during treatment and for 3 months after.
- 哺乳
- Unknown No human milk data; it passes into rat milk. LactMed: as a large protein, milk levels are likely very low and poorly absorbed, but no data yet. US label: breastfeeding not recommended during treatment and for 3 months after the last dose.
已通報的副作用
- Fatigue
- Headache
- Musculoskeletal pain
- Arthralgia
- Dizziness/vertigo
- Nausea
哪些人需要特別留意
- Thromboembolic events reported in beta thalassemia; consider thromboprophylaxis in at-risk patients and monitor.
- Hypertension: monitor blood pressure before each administration and treat with antihypertensives.
- Extramedullary hematopoietic masses in beta thalassemia; monitor and discontinue for serious complications.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Luspatercept 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- IV preparation and dilution
在網頁版免費試用 Pro+ 7 天，無需信用卡。
同類別的其他藥品
常見問題
What is Luspatercept used for?
Luspatercept is a medicine in the class miscellaneous. It is used for Anemia, Myelodysplastic syndromes, Thalassemia.
What side effects have been reported with Luspatercept?
Fatigue, Headache, Musculoskeletal pain, Arthralgia, Dizziness/vertigo, Nausea.
Can Luspatercept be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. May cause fetal harm: in rats and rabbits it caused fetal death, poor growth and malformations. No human data. Do not use in pregnancy; women who could become pregnant need a pregnancy test before starting and effective contraception during treatment and for 3 months after. Breastfeeding: Unknown. No human milk data; it passes into rat milk. LactMed: as a large protein, milk levels are likely very low and poorly absorbed, but no data yet. US label: breastfeeding not recommended during treatment and for 3 months after the last dose.
What does Luspatercept interact with?
MediHelp does not list a checked interaction for Luspatercept yet. Always tell your pharmacist about every medicine you take.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
