藥品參考
Pitavastatin
Pitavastatin is a medicine in the class cardiovascular. It is used for dyslipidemia.
- 藥物類別: Cardiovascular
- 用途: dyslipidemia
最後更新 來源: US FDA label, Base de donnees publique des medicaments (France), ANSM Base de donnees publique des medicaments (RCP, French)
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Cardiovascular
- 常見劑型
- 錠劑
- 常見規格
- 2 mg, 4 mg, 1 mg
- 已知交互作用
- 81 (禁忌併用: 1 · 嚴重: 11 · 中度: 45 · 輕微: 24)
- 商品名
- 24
- 國家與市場
- 4
用途
作用方式
HMG-CoA reductase inhibitor, inhibits rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase
成人常用劑量（仿單摘要）
Hyperlipidemia: Recommended starting dose: 2 mg PO qDay May increase to 4 mg PO qDay if necessary
一般服用方式
Statins are taken by mouth once a day, long term, with blood tests to check the response and liver function.
懷孕與哺乳
- 懷孕
- Unsafe EU labels contraindicate it in pregnancy and in women not using contraception (reduced fetal cholesterol synthesis); stop 1 month before conceiving. US label (2026) no longer does: stop when pregnancy is recognised unless the need is compelling; statin data show no rise in birth defects.
- 哺乳
- Unsafe Not known if it passes into human milk; it passes into rat milk and is 99% protein bound. EU label: contraindicated; US label: not recommended (possible effects on infant lipid metabolism). LactMed: consensus is not to use it; some experts consider pravastatin or rosuvastatin lower risk. Avoid.
已通報的副作用
- Diarrhea
- Constipation
- Back pain
- Myalgia
- Pain in extremity
禁忌症
- Concomitant use of cyclosporine.
- Acute liver failure or decompensated cirrhosis.
- Hypersensitivity to pitavastatin or any excipients; reactions including angioedema, rash, pruritus and urticaria have been reported.
哪些人需要特別留意
- Increased serum transaminases reported; typically, elevations are transient and either resolved or improved on continued therapy or after briefly interrupting therapy
- Myopathy risk factors include: age ≥65 yr, uncontrolled hypothyroidism, renal impairment, coadministration of drugs that decrease statin clearance or add to myopathy risk
- Contraindicated: Coadministration with cyclosporine
Unexplained muscle pain, tenderness or weakness while taking a statin should be reported promptly. Statins are not used in pregnancy, and some other medicines raise their levels and risk.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (81)
- Cyclosporin + Pitavastatin Contraindicated
- Erythromycin + Pitavastatin Major
- Erythromycin base + Pitavastatin Major
- Erythromycin ethylsuccinate + Pitavastatin Major
- Erythromycin lactobionate + Pitavastatin Major
- Erythromycin stearate + Pitavastatin Major
- Gemfibrozil + Pitavastatin Major
- Glecaprevir / pibrentasvir + Pitavastatin Major
- Letermovir + Pitavastatin Major
- Ombitasvir / paritaprevir / ritonavir and dasabuvir + Pitavastatin Major
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Pitavastatin 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
在網頁版免費試用 Pro+ 7 天，無需信用卡。
同類別的其他藥品
常見問題
What is Pitavastatin used for?
Pitavastatin is a medicine in the class cardiovascular. It is used for Dyslipidemia, Hypercholesterolemia.
What side effects have been reported with Pitavastatin?
Diarrhea, Constipation, Back pain, Myalgia, Pain in extremity.
Can Pitavastatin be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. EU labels contraindicate it in pregnancy and in women not using contraception (reduced fetal cholesterol synthesis); stop 1 month before conceiving. US label (2026) no longer does: stop when pregnancy is recognised unless the need is compelling; statin data show no rise in birth defects. Breastfeeding: Unsafe. Not known if it passes into human milk; it passes into rat milk and is 99% protein bound. EU label: contraindicated; US label: not recommended (possible effects on infant lipid metabolism). LactMed: consensus is not to use it; some experts consider pravastatin or rosuvastatin lower risk. Avoid.
What does Pitavastatin interact with?
MediHelp lists 81 known interactions for Pitavastatin. Contraindicated: 1 · Major: 11 · Moderate: 45 · Minor: 24. The most serious include Cyclosporin, Erythromycin, Erythromycin base.
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