藥品參考
Plerixafor
Plerixafor is a medicine in the class miscellaneous. It is used for multiple myeloma.
- 藥物類別: Miscellaneous
- 用途: multiple myeloma
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Miscellaneous
- ATC 代碼
- L03AX16
- 常見劑型
- 注射劑
- 常見規格
- 24 mg/1.2 ml
- 商品名
- 3
- 國家與市場
- 2
用途
作用方式
Plerixafor inhibits the CXCR4 chemokine receptor and blocks binding of its ligand SDF-1α, which is involved in the homing of hematopoietic stem cells to the marrow. This results in leukocytosis and increased circulating hematopoietic progenitor cells.
成人常用劑量（仿單摘要）
HSC mobilization (NHL or MM, with filgrastim): 20 mg fixed dose or 0.24 mg/kg subcutaneously for weight ≤83 kg, about 11 hours before each apheresis, for up to 4 consecutive days; start after 4 days of filgrastim
懷孕與哺乳
- 懷孕
- Unsafe Can cause fetal harm based on animal studies (embryo-fetal mortality, structural abnormalities in rats). Use effective contraception during treatment and for one week after the final dose.
- 哺乳
- Unsafe No human milk data. Breastfeeding is not recommended during treatment and for one week after the final dose.
已通報的副作用
- Diarrhea
- Nausea
- Injection site reactions
- Fatigue
- Headache
- Arthralgia
禁忌症
- History of hypersensitivity to plerixafor
哪些人需要特別留意
- Anaphylactic shock and serious hypersensitivity reactions: observe for at least 30 minutes and until clinically stable; have anaphylaxis treatment available
- May mobilize leukemic cells; not intended for use in patients with leukemia
- Leukocytosis and thrombocytopenia: monitor white blood cell and platelet counts
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
同類別的其他藥品
常見問題
What is Plerixafor used for?
Plerixafor is a medicine in the class miscellaneous. It is used for Multiple myeloma, Non-hodgkin lymphoma.
What side effects have been reported with Plerixafor?
Diarrhea, Nausea, Injection site reactions, Fatigue, Headache, Arthralgia.
Can Plerixafor be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Can cause fetal harm based on animal studies (embryo-fetal mortality, structural abnormalities in rats). Use effective contraception during treatment and for one week after the final dose. Breastfeeding: Unsafe. No human milk data. Breastfeeding is not recommended during treatment and for one week after the final dose.
What does Plerixafor interact with?
MediHelp does not list a checked interaction for Plerixafor yet. Always tell your pharmacist about every medicine you take.
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