藥物交互作用
Abrocitinib + Ticlopidine
嚴重程度: 嚴重
Abrocitinib and Ticlopidine: major interaction.
最後更新
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摘要
Abrocitinib lowers platelet count and function early in treatment, and ticlopidine also impairs platelet function and can cause thrombocytopenia. Together they increase bleeding risk. Labeling advises against antiplatelets except low-dose aspirin in the first three months.
用白話說明這項交互作用的意義
Abrocitinib and Ticlopidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Abrocitinib belongs to Miscellaneous; Ticlopidine belongs to Cardiovascular.
為什麼會發生
Additive impairment of platelet function and count.
處置方式
Avoid the combination in the first three months of abrocitinib. Monitor platelet counts and for bleeding if it cannot be avoided.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Ticlopidine 的其他交互作用
Abrocitinib 的其他交互作用
常見問題
Can I take Abrocitinib with Ticlopidine?
MediHelp rates the interaction as major. Abrocitinib and Ticlopidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Abrocitinib lowers platelet count and function early in treatment, and ticlopidine also impairs platelet function and can cause thrombocytopenia. Together they increase bleeding risk. Labeling advises against antiplatelets except low-dose aspirin in the first three months.
How serious is the interaction between Abrocitinib and Ticlopidine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in the first three months of abrocitinib. Monitor platelet counts and for bleeding if it cannot be avoided.
What other medicines interact with Ticlopidine?
MediHelp also lists interactions of Ticlopidine with, for example, Mavacamten, Acetylsalicylic acid, Apixaban. The full list is on the Ticlopidine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
