藥物交互作用
Apixaban + Ticlopidine
嚴重程度: 嚴重
Apixaban and Ticlopidine: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Ticlopidine is a potent antiplatelet drug and adds to apixaban's bleeding risk. Ticlopidine also carries hematologic toxicity, further complicating bleeding assessment.
用白話說明這項交互作用的意義
Apixaban and Ticlopidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Apixaban belongs to Cardiovascular; Ticlopidine belongs to Cardiovascular.
為什麼會發生
Additive effects of P2Y12 receptor blockade and factor Xa inhibition.
處置方式
Avoid if possible; clopidogrel is generally preferred when an antiplatelet is needed. If combined, monitor for bleeding and blood counts.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Apixaban 的其他交互作用
Ticlopidine 的其他交互作用
常見問題
Can I take Apixaban with Ticlopidine?
MediHelp rates the interaction as major. Apixaban and Ticlopidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ticlopidine is a potent antiplatelet drug and adds to apixaban's bleeding risk. Ticlopidine also carries hematologic toxicity, further complicating bleeding assessment.
How serious is the interaction between Apixaban and Ticlopidine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible; clopidogrel is generally preferred when an antiplatelet is needed. If combined, monitor for bleeding and blood counts.
What other medicines interact with Apixaban?
MediHelp also lists interactions of Apixaban with, for example, Dabigatran, Defibrotide, Edoxaban. The full list is on the Apixaban page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
