藥品參考
Ticlopidine
Ticlopidine is a medicine in the class cardiovascular. It is used for coronary artery stent thrombosis.
- 藥物類別: Cardiovascular
- 用途: coronary artery stent thrombosis
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Cardiovascular
- 常見劑型
- 錠劑
- 常見規格
- 250 mg
- 已知交互作用
- 113 (禁忌併用: 1 · 嚴重: 32 · 中度: 52 · 輕微: 28)
- 商品名
- 3
- 國家與市場
- 2
用途
作用方式
Platelet aggregation inhibitor; reversibly interacts with the platelet P2Y12 ADP-receptor to prevent signal transduction and platelet activation
成人常用劑量（仿單摘要）
Stroke: 250 mg PO q12hr with food
懷孕與哺乳
- 懷孕
- Unknown Largely withdrawn (blood disorders); clopidogrel has replaced it. Animal studies at high doses showed no birth defects; human data are very limited. Avoid in pregnancy; if an antiplatelet is needed, clopidogrel or low-dose aspirin is preferred.
- 哺乳
- Unknown Not known if it passes into milk; no LactMed record. The old US label advised stopping the drug or nursing. Because of its serious blood side effects (neutropenia, TTP), avoid while breastfeeding and use an alternative.
已通報的副作用
- Diarrhea
- Nausea
- Rash
- Dyspepsia
- Elevated alkaline phosphatase
黑框警語
- May cause life-threatening hematologic events, including neutropenia, agranulocytosis, thrombocytopenia purpura, and aplastic anemia
禁忌症
- Neutropenia, thrombocytopenia, hemostatic disorder or active bleeding (GI bleed, ICH), severe hepatic impairment, history of either thrombotic thrombocytopenic purpura (TTP) or aplastic anemia
- Current use of other anticoagulant drugs
哪些人需要特別留意
- Increases serum chlesterol & triglyceride concentrations
- Patients with lesions that have a propensity to bleed
- Due to risk of adverse hematologic events, for stroke prevention use only in ASA-intolerant patients
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (113)
- Mavacamten + Ticlopidine Contraindicated
- Abrocitinib + Ticlopidine Major
- Acetylsalicylic acid + Ticlopidine Major
- Apixaban + Ticlopidine Major
- Aspirin + Ticlopidine Major
- Aspirin / citric acid / sodium bicarbonate + Ticlopidine Major
- Aspirin rectal + Ticlopidine Major
- Betrixaban + Ticlopidine Major
- Carbamazepine + Ticlopidine Major
- Cilostazol + Ticlopidine Major
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Ticlopidine 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- Pharmacokinetics
- Patient counselling points
- Food interactions
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
常見問題
What is Ticlopidine used for?
Ticlopidine is a medicine in the class cardiovascular. It is used for Coronary artery stent thrombosis, Stroke.
What side effects have been reported with Ticlopidine?
Diarrhea, Nausea, Rash, Dyspepsia, Elevated alkaline phosphatase. Serious warning: May cause life-threatening hematologic events, including neutropenia, agranulocytosis, thrombocytopenia purpura, and aplastic anemia
Can Ticlopidine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Largely withdrawn (blood disorders); clopidogrel has replaced it. Animal studies at high doses showed no birth defects; human data are very limited. Avoid in pregnancy; if an antiplatelet is needed, clopidogrel or low-dose aspirin is preferred. Breastfeeding: Unknown. Not known if it passes into milk; no LactMed record. The old US label advised stopping the drug or nursing. Because of its serious blood side effects (neutropenia, TTP), avoid while breastfeeding and use an alternative.
What does Ticlopidine interact with?
MediHelp lists 113 known interactions for Ticlopidine. Contraindicated: 1 · Major: 32 · Moderate: 52 · Minor: 28. The most serious include Mavacamten, Abrocitinib, Acetylsalicylic acid.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
