藥物交互作用
Aluminum hydroxide + Chenodeoxycholic acid
嚴重程度: 中度
Aluminum hydroxide and Chenodeoxycholic acid: moderate interaction.
最後更新
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摘要
Aluminium-containing antacids can adsorb bile acids in the gut. This reduces absorption of chenodeoxycholic acid and may weaken its therapeutic effect.
用白話說明這項交互作用的意義
Aluminum hydroxide and Chenodeoxycholic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Chenodeoxycholic acid belongs to Gastrointestinal Tract.
為什麼會發生
Adsorption of bile acid by aluminium hydroxide in the intestinal lumen reduces absorption.
處置方式
Separate the doses by at least 2 hours. Monitor clinical or biochemical response if concomitant use continues.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Chenodeoxycholic acid 的其他交互作用
Aluminum hydroxide 的其他交互作用
常見問題
Can I take Aluminum hydroxide with Chenodeoxycholic acid?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Chenodeoxycholic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminium-containing antacids can adsorb bile acids in the gut. This reduces absorption of chenodeoxycholic acid and may weaken its therapeutic effect.
How serious is the interaction between Aluminum hydroxide and Chenodeoxycholic acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate the doses by at least 2 hours. Monitor clinical or biochemical response if concomitant use continues.
What other medicines interact with Chenodeoxycholic acid?
MediHelp also lists interactions of Chenodeoxycholic acid with, for example, Cyclosporin, Sirolimus, Colestipol. The full list is on the Chenodeoxycholic acid page.
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