藥物交互作用
Chenodeoxycholic acid + Colestipol
嚴重程度: 中度
Chenodeoxycholic acid and Colestipol: moderate interaction.
最後更新
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摘要
Colestipol is a bile acid sequestrant that binds bile acids in the intestine. It reduces absorption of chenodeoxycholic acid and may lessen its efficacy.
用白話說明這項交互作用的意義
Chenodeoxycholic acid and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chenodeoxycholic acid belongs to Gastrointestinal Tract; Colestipol belongs to Cardiovascular.
為什麼會發生
Colestipol binds chenodeoxycholic acid in the gut, preventing absorption and enterohepatic recirculation.
處置方式
Give chenodeoxycholic acid at least 2 hours before or after colestipol. Monitor response, or choose an alternative lipid-lowering agent.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Chenodeoxycholic acid 的其他交互作用
Colestipol 的其他交互作用
常見問題
Can I take Chenodeoxycholic acid with Colestipol?
MediHelp rates the interaction as moderate. Chenodeoxycholic acid and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol is a bile acid sequestrant that binds bile acids in the intestine. It reduces absorption of chenodeoxycholic acid and may lessen its efficacy.
How serious is the interaction between Chenodeoxycholic acid and Colestipol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give chenodeoxycholic acid at least 2 hours before or after colestipol. Monitor response, or choose an alternative lipid-lowering agent.
What other medicines interact with Chenodeoxycholic acid?
MediHelp also lists interactions of Chenodeoxycholic acid with, for example, Cyclosporin, Sirolimus, Aluminum hydroxide. The full list is on the Chenodeoxycholic acid page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
