藥物交互作用
Aluminum hydroxide + Cholecalciferol
嚴重程度: 中度
Aluminum hydroxide and Cholecalciferol: moderate interaction.
最後更新
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摘要
Vitamin D increases intestinal absorption of aluminum, and chronic use of aluminum-containing antacids can lead to aluminum accumulation. This is most important in renal impairment, where aluminum toxicity can cause bone disease and neurotoxicity.
用白話說明這項交互作用的意義
Aluminum hydroxide and Cholecalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Cholecalciferol belongs to Musculoskeletal.
為什麼會發生
Vitamin D enhances gastrointestinal aluminum absorption, and aluminum is poorly excreted in renal failure.
處置方式
Avoid long-term aluminum antacids in patients taking vitamin D, particularly with renal impairment; use a non-aluminum alternative.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cholecalciferol 的其他交互作用
Aluminum hydroxide 的其他交互作用
常見問題
Can I take Aluminum hydroxide with Cholecalciferol?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Cholecalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vitamin D increases intestinal absorption of aluminum, and chronic use of aluminum-containing antacids can lead to aluminum accumulation. This is most important in renal impairment, where aluminum toxicity can cause bone disease and neurotoxicity.
How serious is the interaction between Aluminum hydroxide and Cholecalciferol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid long-term aluminum antacids in patients taking vitamin D, particularly with renal impairment; use a non-aluminum alternative.
What other medicines interact with Cholecalciferol?
MediHelp also lists interactions of Cholecalciferol with, for example, Digoxin, Calcium acetate, Calcium Carbonate. The full list is on the Cholecalciferol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。