藥物交互作用
Cholecalciferol + Digoxin
嚴重程度: 嚴重
Cholecalciferol and Digoxin: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Vitamin D-induced hypercalcemia increases myocardial sensitivity to digoxin and can precipitate arrhythmias. The risk is greatest with high-dose vitamin D or active analogs.
用白話說明這項交互作用的意義
Cholecalciferol and Digoxin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cholecalciferol belongs to Musculoskeletal; Digoxin belongs to Cardiovascular.
為什麼會發生
Hypercalcemia augments digoxin's cardiac effects, increasing digoxin toxicity risk.
處置方式
Monitor serum calcium and digoxin toxicity signs, and keep vitamin D doses modest; adjust therapy if calcium rises.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cholecalciferol 的其他交互作用
Digoxin 的其他交互作用
常見問題
Can I take Cholecalciferol with Digoxin?
MediHelp rates the interaction as major. Cholecalciferol and Digoxin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Vitamin D-induced hypercalcemia increases myocardial sensitivity to digoxin and can precipitate arrhythmias. The risk is greatest with high-dose vitamin D or active analogs.
How serious is the interaction between Cholecalciferol and Digoxin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium and digoxin toxicity signs, and keep vitamin D doses modest; adjust therapy if calcium rises.
What other medicines interact with Cholecalciferol?
MediHelp also lists interactions of Cholecalciferol with, for example, Aluminum hydroxide, Calcium acetate, Calcium Carbonate. The full list is on the Cholecalciferol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
