藥物交互作用
Aluminum hydroxide + Omadacycline
嚴重程度: 中度
Aluminum hydroxide and Omadacycline: moderate interaction.
最後更新
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摘要
Aluminum binds omadacycline in the gut and reduces its absorption. This may reduce antibacterial efficacy.
用白話說明這項交互作用的意義
Aluminum hydroxide and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Omadacycline belongs to Anti Bacterial.
為什麼會發生
Chelation of the tetracycline by polyvalent aluminum cations forms poorly absorbed complexes.
處置方式
Separate dosing; take omadacycline at least 4 hours before or 2 hours after antacids, per labeling. Monitor clinical response.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Aluminum hydroxide 的其他交互作用
Omadacycline 的其他交互作用
常見問題
Can I take Aluminum hydroxide with Omadacycline?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminum binds omadacycline in the gut and reduces its absorption. This may reduce antibacterial efficacy.
How serious is the interaction between Aluminum hydroxide and Omadacycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate dosing; take omadacycline at least 4 hours before or 2 hours after antacids, per labeling. Monitor clinical response.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
