藥物交互作用
Amoxicillin-clavulanic acid + Omadacycline
嚴重程度: 中度
Amoxicillin-clavulanic acid and Omadacycline: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Omadacycline is a bacteriostatic tetracycline that may theoretically blunt penicillin bactericidal effects. There is limited clinical evidence of harm. Relevance is greatest in serious infections.
用白話說明這項交互作用的意義
Amoxicillin-clavulanic acid and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amoxicillin-clavulanic acid belongs to Anti Bacterial; Omadacycline belongs to Anti Bacterial.
為什麼會發生
Pharmacodynamic antagonism: inhibition of bacterial growth reduces the activity of beta-lactams that act on dividing cells.
處置方式
Avoid combining for severe infections unless dual therapy is clearly justified. Monitor clinical response if used together.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amoxicillin-clavulanic acid 的其他交互作用
Omadacycline 的其他交互作用
常見問題
Can I take Amoxicillin-clavulanic acid with Omadacycline?
MediHelp rates the interaction as moderate. Amoxicillin-clavulanic acid and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Omadacycline is a bacteriostatic tetracycline that may theoretically blunt penicillin bactericidal effects. There is limited clinical evidence of harm. Relevance is greatest in serious infections.
How serious is the interaction between Amoxicillin-clavulanic acid and Omadacycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining for severe infections unless dual therapy is clearly justified. Monitor clinical response if used together.
What other medicines interact with Amoxicillin-clavulanic acid?
MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Pretomanid. The full list is on the Amoxicillin-clavulanic acid page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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