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藥物交互作用

Aminolevulinic acid + Tetracycline

嚴重程度: 中度

Aminolevulinic acid and Tetracycline: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Oral aminolevulinic acid causes protoporphyrin accumulation and photosensitivity, and tetracyclines are also phototoxic. Using them together may increase the risk of severe phototoxic skin reactions.

用白話說明這項交互作用的意義

Aminolevulinic acid and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Aminolevulinic acid belongs to Miscellaneous; Tetracycline belongs to Anti Bacterial.

證據等級: Low

為什麼會發生

Additive phototoxicity from photosensitizing agents.

處置方式

Avoid giving tetracycline during the 24 hours around aminolevulinic acid administration and counsel the patient on strict sun and bright light protection.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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常見問題

Can I take Aminolevulinic acid with Tetracycline?

MediHelp rates the interaction as moderate. Aminolevulinic acid and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral aminolevulinic acid causes protoporphyrin accumulation and photosensitivity, and tetracyclines are also phototoxic. Using them together may increase the risk of severe phototoxic skin reactions.

How serious is the interaction between Aminolevulinic acid and Tetracycline?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving tetracycline during the 24 hours around aminolevulinic acid administration and counsel the patient on strict sun and bright light protection.

What other medicines interact with Tetracycline?

MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Methoxyflurane, Isotretinoin. The full list is on the Tetracycline page.

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