藥物交互作用
Aminolevulinic acid + Tretinoin
嚴重程度: 中度
Aminolevulinic acid and Tretinoin: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Oral aminolevulinic acid causes protoporphyrin IX accumulation and photosensitivity. Tretinoin can increase skin sensitivity to light, so phototoxic reactions such as severe sunburn may be worse. Systemic tretinoin is the main concern; topical use adds little.
用白話說明這項交互作用的意義
Aminolevulinic acid and Tretinoin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aminolevulinic acid belongs to Miscellaneous; Tretinoin belongs to Dermatology.
為什麼會發生
Additive photosensitizing effects from two agents that increase the skin's reactivity to light.
處置方式
Counsel strict photoprotection and avoid sun and bright light exposure after aminolevulinic acid for the period specified in labeling. Avoid giving other photosensitizers perioperatively around dosing.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Tretinoin 的其他交互作用
Aminolevulinic acid 的其他交互作用
常見問題
Can I take Aminolevulinic acid with Tretinoin?
MediHelp rates the interaction as moderate. Aminolevulinic acid and Tretinoin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral aminolevulinic acid causes protoporphyrin IX accumulation and photosensitivity. Tretinoin can increase skin sensitivity to light, so phototoxic reactions such as severe sunburn may be worse. Systemic tretinoin is the main concern; topical use adds little.
How serious is the interaction between Aminolevulinic acid and Tretinoin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel strict photoprotection and avoid sun and bright light exposure after aminolevulinic acid for the period specified in labeling. Avoid giving other photosensitizers perioperatively around dosing.
What other medicines interact with Tretinoin?
MediHelp also lists interactions of Tretinoin with, for example, Doxycycline, Minocycline, Omadacycline. The full list is on the Tretinoin page.
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