藥物交互作用
Amiodarone + Ibutilide
嚴重程度: 禁忌併用
Amiodarone and Ibutilide: contraindicated interaction.
最後更新
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摘要
Both are class III antiarrhythmics that prolong repolarization. Together they raise the risk of prolonged refractoriness, marked QT prolongation and torsades de pointes.
用白話說明這項交互作用的意義
Amiodarone and Ibutilide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Amiodarone belongs to Cardiovascular; Ibutilide belongs to Cardiovascular.
為什麼會發生
Additive blockade of cardiac potassium channels causing QT prolongation.
處置方式
Do not give ibutilide to patients on amiodarone, nor other class III agents during or soon after the infusion. Use electrical cardioversion or another option.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Amiodarone 的其他交互作用
Ibutilide 的其他交互作用
常見問題
Can I take Amiodarone with Ibutilide?
MediHelp rates the interaction as contraindicated. Amiodarone and Ibutilide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both are class III antiarrhythmics that prolong repolarization. Together they raise the risk of prolonged refractoriness, marked QT prolongation and torsades de pointes.
How serious is the interaction between Amiodarone and Ibutilide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give ibutilide to patients on amiodarone, nor other class III agents during or soon after the infusion. Use electrical cardioversion or another option.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
