藥物交互作用
Amisulpride + Ibutilide
嚴重程度: 禁忌併用
Amisulpride and Ibutilide: contraindicated interaction.
最後更新
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摘要
Ibutilide is a class III antiarrhythmic with a high risk of torsades de pointes, and amisulpride adds further QT prolongation. The combination can cause life-threatening arrhythmia.
用白話說明這項交互作用的意義
Amisulpride and Ibutilide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Amisulpride belongs to Central Nervous System; Ibutilide belongs to Cardiovascular.
為什麼會發生
Additive potassium channel blockade producing marked delayed repolarization.
處置方式
Do not use together; hold amisulpride or choose another cardioversion strategy. If ibutilide is given, continuous ECG monitoring is required.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Amisulpride 的其他交互作用
Ibutilide 的其他交互作用
常見問題
Can I take Amisulpride with Ibutilide?
MediHelp rates the interaction as contraindicated. Amisulpride and Ibutilide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ibutilide is a class III antiarrhythmic with a high risk of torsades de pointes, and amisulpride adds further QT prolongation. The combination can cause life-threatening arrhythmia.
How serious is the interaction between Amisulpride and Ibutilide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; hold amisulpride or choose another cardioversion strategy. If ibutilide is given, continuous ECG monitoring is required.
What other medicines interact with Amisulpride?
MediHelp also lists interactions of Amisulpride with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Amisulpride page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
