藥物交互作用
Amisulpride + Encorafenib
嚴重程度: 嚴重
Amisulpride and Encorafenib: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Encorafenib can prolong the QT interval in a dose-dependent manner. Adding amisulpride, which also prolongs QTc, increases the likelihood of arrhythmia.
用白話說明這項交互作用的意義
Amisulpride and Encorafenib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amisulpride belongs to Central Nervous System; Encorafenib belongs to Oncology.
為什麼會發生
Additive QT prolongation.
處置方式
Avoid if possible; otherwise monitor ECG and electrolytes at baseline and during treatment. Interrupt or reduce the dose of encorafenib if QTc rises substantially.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Amisulpride 的其他交互作用
Encorafenib 的其他交互作用
常見問題
Can I take Amisulpride with Encorafenib?
MediHelp rates the interaction as major. Amisulpride and Encorafenib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Encorafenib can prolong the QT interval in a dose-dependent manner. Adding amisulpride, which also prolongs QTc, increases the likelihood of arrhythmia.
How serious is the interaction between Amisulpride and Encorafenib?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible; otherwise monitor ECG and electrolytes at baseline and during treatment. Interrupt or reduce the dose of encorafenib if QTc rises substantially.
What other medicines interact with Amisulpride?
MediHelp also lists interactions of Amisulpride with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Amisulpride page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
