藥物交互作用
Amoxapine + Budesonide-formoterol
嚴重程度: 嚴重
Amoxapine and Budesonide-formoterol: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Tricyclic antidepressants like amoxapine can potentiate the cardiovascular effects of formoterol, causing tachycardia and arrhythmia. Both can also prolong the QT interval.
用白話說明這項交互作用的意義
Amoxapine and Budesonide-formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Tricyclic inhibition of norepinephrine reuptake and additive QT prolongation potentiate beta-agonist cardiac effects.
處置方式
Use with close ECG, heart rate and blood pressure monitoring, or choose an alternative antidepressant. Check potassium in patients with other risk factors.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Budesonide-formoterol 的其他交互作用
常見問題
Can I take Amoxapine with Budesonide-formoterol?
MediHelp rates the interaction as major. Amoxapine and Budesonide-formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Tricyclic antidepressants like amoxapine can potentiate the cardiovascular effects of formoterol, causing tachycardia and arrhythmia. Both can also prolong the QT interval.
How serious is the interaction between Amoxapine and Budesonide-formoterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use with close ECG, heart rate and blood pressure monitoring, or choose an alternative antidepressant. Check potassium in patients with other risk factors.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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