藥物交互作用
Amisulpride + Budesonide-formoterol
嚴重程度: 嚴重
Amisulpride and Budesonide-formoterol: major interaction.
最後更新
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摘要
Amisulpride causes dose-related QT prolongation, and formoterol can add tachycardia, hypokalemia and QT effects. Together they raise the risk of torsades de pointes in susceptible patients.
用白話說明這項交互作用的意義
Amisulpride and Budesonide-formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amisulpride belongs to Central Nervous System; Budesonide-formoterol belongs to Respiratory.
為什麼會發生
Additive effects on cardiac repolarization, with beta-agonist-induced hypokalemia.
處置方式
Obtain a baseline ECG and monitor it during co-therapy, and correct potassium and magnesium. Consider an alternative if other QT risk factors are present.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Budesonide-formoterol 的其他交互作用
Amisulpride 的其他交互作用
常見問題
Can I take Amisulpride with Budesonide-formoterol?
MediHelp rates the interaction as major. Amisulpride and Budesonide-formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amisulpride causes dose-related QT prolongation, and formoterol can add tachycardia, hypokalemia and QT effects. Together they raise the risk of torsades de pointes in susceptible patients.
How serious is the interaction between Amisulpride and Budesonide-formoterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor it during co-therapy, and correct potassium and magnesium. Consider an alternative if other QT risk factors are present.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amitriptyline. The full list is on the Budesonide-formoterol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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