藥物交互作用
Amiodarone + Budesonide-formoterol
嚴重程度: 嚴重
Amiodarone and Budesonide-formoterol: major interaction.
最後更新
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摘要
Amiodarone markedly prolongs the QT interval and formoterol can add to QT effects and cause hypokalemia and tachyarrhythmias. Together they may increase the risk of torsades de pointes, particularly with higher formoterol doses or electrolyte disturbances.
用白話說明這項交互作用的意義
Amiodarone and Budesonide-formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amiodarone belongs to Cardiovascular; Budesonide-formoterol belongs to Respiratory.
為什麼會發生
Additive QT prolongation, with beta-2 agonist-induced hypokalemia increasing arrhythmia susceptibility.
處置方式
Monitor ECG and keep potassium and magnesium within normal range. Use the lowest effective formoterol dose and avoid other QT-prolonging drugs.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Budesonide-formoterol 的其他交互作用
Amiodarone 的其他交互作用
常見問題
Can I take Amiodarone with Budesonide-formoterol?
MediHelp rates the interaction as major. Amiodarone and Budesonide-formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amiodarone markedly prolongs the QT interval and formoterol can add to QT effects and cause hypokalemia and tachyarrhythmias. Together they may increase the risk of torsades de pointes, particularly with higher formoterol doses or electrolyte disturbances.
How serious is the interaction between Amiodarone and Budesonide-formoterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and keep potassium and magnesium within normal range. Use the lowest effective formoterol dose and avoid other QT-prolonging drugs.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amisulpride, Amitriptyline. The full list is on the Budesonide-formoterol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
