藥物交互作用
Amphotericin b + Corticotropin
嚴重程度: 中度
Amphotericin b and Corticotropin: moderate interaction.
最後更新
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摘要
Both amphotericin B and corticotropin promote potassium loss. Together they can cause severe hypokalemia, which may lead to arrhythmias and muscle weakness, and may be worsened by cardiac glycosides.
用白話說明這項交互作用的意義
Amphotericin b and Corticotropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amphotericin b belongs to Anti Fungals; Corticotropin belongs to Endocrine.
為什麼會發生
Additive renal potassium wasting (amphotericin tubular effect plus mineralocorticoid effect of corticotropin).
處置方式
Monitor serum potassium and cardiac status, and supplement potassium as needed. Check magnesium too.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amphotericin b 的其他交互作用
Corticotropin 的其他交互作用
常見問題
Can I take Amphotericin b with Corticotropin?
MediHelp rates the interaction as moderate. Amphotericin b and Corticotropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both amphotericin B and corticotropin promote potassium loss. Together they can cause severe hypokalemia, which may lead to arrhythmias and muscle weakness, and may be worsened by cardiac glycosides.
How serious is the interaction between Amphotericin b and Corticotropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and cardiac status, and supplement potassium as needed. Check magnesium too.
What other medicines interact with Amphotericin b?
MediHelp also lists interactions of Amphotericin b with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Amphotericin b page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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