藥物交互作用
Amphotericin b liposomal + Oxaliplatin
嚴重程度: 中度
Amphotericin b liposomal and Oxaliplatin: moderate interaction.
最後更新
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摘要
Amphotericin B can cause nephrotoxicity, electrolyte loss and infusion reactions. Oxaliplatin could add to renal or infusion-related problems, but the clinical data supporting this are limited.
用白話說明這項交互作用的意義
Amphotericin b liposomal and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amphotericin b liposomal belongs to Anti Fungals; Oxaliplatin belongs to Oncology.
為什麼會發生
Possible additive nephrotoxicity; the mechanism is not well established.
處置方式
Monitor renal function, potassium and magnesium during co-treatment. Watch for infusion reactions such as bronchospasm and hypotension.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Oxaliplatin 的其他交互作用
- Adenovirus types 4 and 7 live + Oxaliplatin 禁忌併用
- Bcg vaccine live + Oxaliplatin 禁忌併用
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin 禁忌併用
- Measles mumps and rubella vaccine live + Oxaliplatin 禁忌併用
- Measles mumps and rubella vaccine + Oxaliplatin 禁忌併用
- Measles mumps rubella and varicella vaccine live + Oxaliplatin 禁忌併用
Amphotericin b liposomal 的其他交互作用
常見問題
Can I take Amphotericin b liposomal with Oxaliplatin?
MediHelp rates the interaction as moderate. Amphotericin b liposomal and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amphotericin B can cause nephrotoxicity, electrolyte loss and infusion reactions. Oxaliplatin could add to renal or infusion-related problems, but the clinical data supporting this are limited.
How serious is the interaction between Amphotericin b liposomal and Oxaliplatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function, potassium and magnesium during co-treatment. Watch for infusion reactions such as bronchospasm and hypotension.
What other medicines interact with Oxaliplatin?
MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Oxaliplatin page.
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