藥物交互作用
Ampicillin-sulbactam + Bcg vaccine live
嚴重程度: 中度
Ampicillin-sulbactam and Bcg vaccine live: moderate interaction.
最後更新
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摘要
Live BCG contains viable bacteria, and antibiotics active against them can reduce vaccine take. Ampicillin has limited activity against BCG, but the labeling for live bacterial vaccines advises avoiding concurrent antibiotics.
用白話說明這項交互作用的意義
Ampicillin-sulbactam and Bcg vaccine live can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Antibacterial activity may reduce replication of the live vaccine organism, lessening the immune response.
處置方式
Defer BCG vaccination until antibiotic therapy is complete, where the vaccine is not urgent.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Ampicillin-sulbactam 的其他交互作用
常見問題
Can I take Ampicillin-sulbactam with Bcg vaccine live?
MediHelp rates the interaction as moderate. Ampicillin-sulbactam and Bcg vaccine live can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Live BCG contains viable bacteria, and antibiotics active against them can reduce vaccine take. Ampicillin has limited activity against BCG, but the labeling for live bacterial vaccines advises avoiding concurrent antibiotics.
How serious is the interaction between Ampicillin-sulbactam and Bcg vaccine live?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Defer BCG vaccination until antibiotic therapy is complete, where the vaccine is not urgent.
What other medicines interact with Ampicillin-sulbactam?
MediHelp also lists interactions of Ampicillin-sulbactam with, for example, Methotrexate, Allopurinol, Chloramphenicol. The full list is on the Ampicillin-sulbactam page.
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