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藥品參考

Ampicillin-sulbactam

Ampicillin-sulbactam is a medicine in the class anti bacterial. It is used for cellulitis.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Anti Bacterial
常見劑型
注射劑, 錠劑, 口服懸液, 粉劑
常見規格
375 mg, 750 mg, 1500 mg
已知交互作用
45 (嚴重: 1 · 中度: 15 · 輕微: 29)
商品名
44
國家與市場
3

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Drug combination of beta-lactamase inhibitor with ampicillin; interferes with bacterial cell wall synthesis during active replication, causing bactericidal activity against susceptible organisms; alternative to amoxicillin when unable to take medication orally; covers skin, enteric flora, and anaerobes; not ideal for nosocomial pathogens.

成人常用劑量(仿單摘要)

Gynecologic Infections: 1.5 g (1 g ampicillin + 0.5 g sulbactam) to 3 g (2 g ampicillin + 1 g sulbactam) IV/IM q6hr; not to exceed 12 g/day

僅摘錄仿單中第一行劑量說明;完整的劑量內容請見 App。

一般服用方式

Penicillin antibiotics are taken by mouth or given by injection at regular intervals for a set number of days; the course should be completed even when symptoms improve early.

確切的劑量、服用時間與療程長短,由開立處方者及產品仿單決定;登入後,MediHelp 會顯示完整的劑量內容。

懷孕與哺乳

懷孕
Safe Ampicillin and sulbactam cross the placenta; studies show no harm, and penicillins are widely used in pregnancy. Considered a safe choice when needed.
哺乳
Safe Both components pass into milk in small amounts. Acceptable; watch the infant for diarrhoea, thrush or rash.

已通報的副作用

  • Diarrhea
  • IM injection site pain
  • IV injection site pain
  • Thrombophlebitis

禁忌症

  • Hypersensitivity to drug or components
  • Patients with previous history of cholestatic jaundice/hepatic dysfunction associated with ampicillin sulbactam

哪些人需要特別留意

  • Patients with previous history of cholestatic jaundice/hepatic dysfunction associated with ampicillin sulbactam
  • A generalized dull red maculopapular rash may occur in 5-10% of children 3-14 days after initiating therapy

Anyone who has had an allergic reaction to a penicillin or another beta-lactam antibiotic must tell the prescriber before taking one. Severe or persistent diarrhoea during or after a course needs medical advice.

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。

重要交互作用 (45)

All 45 interactions, with severity and what to do

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可開啟 Ampicillin-sulbactam 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • Paediatric dosing
  • Pharmacokinetics
  • Patient counselling points
  • Food interactions
  • IV preparation and dilution

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同類別的其他藥品

常見問題

What is Ampicillin-sulbactam used for?

Ampicillin-sulbactam is a medicine in the class anti bacterial. It is used for Cellulitis, Gynecologic infections, Intra-abdominal infections, Skin infections, Urinary tract infections.

What side effects have been reported with Ampicillin-sulbactam?

Diarrhea, IM injection site pain, IV injection site pain, Thrombophlebitis.

Can Ampicillin-sulbactam be taken in pregnancy or while breastfeeding?

Pregnancy: Safe. Ampicillin and sulbactam cross the placenta; studies show no harm, and penicillins are widely used in pregnancy. Considered a safe choice when needed. Breastfeeding: Safe. Both components pass into milk in small amounts. Acceptable; watch the infant for diarrhoea, thrush or rash.

What does Ampicillin-sulbactam interact with?

MediHelp lists 45 known interactions for Ampicillin-sulbactam. Major: 1 · Moderate: 15 · Minor: 29. The most serious include Methotrexate, Allopurinol, Bcg vaccine live.

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