藥物交互作用
Ampicillin-sulbactam + Cholera vaccine
嚴重程度: 中度
Ampicillin-sulbactam and Cholera vaccine: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Oral live attenuated cholera vaccine contains a living bacterial strain that antibiotics can kill. Recent antibiotic exposure may therefore reduce vaccine take and protection.
用白話說明這項交互作用的意義
Ampicillin-sulbactam and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Antibacterial activity against the live attenuated vaccine strain impairs colonisation and immune response.
處置方式
Do not give the vaccine within 14 days after systemic antibiotics. Delay vaccination until the interval has passed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Ampicillin-sulbactam 的其他交互作用
常見問題
Can I take Ampicillin-sulbactam with Cholera vaccine?
MediHelp rates the interaction as moderate. Ampicillin-sulbactam and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral live attenuated cholera vaccine contains a living bacterial strain that antibiotics can kill. Recent antibiotic exposure may therefore reduce vaccine take and protection.
How serious is the interaction between Ampicillin-sulbactam and Cholera vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the vaccine within 14 days after systemic antibiotics. Delay vaccination until the interval has passed.
What other medicines interact with Ampicillin-sulbactam?
MediHelp also lists interactions of Ampicillin-sulbactam with, for example, Methotrexate, Allopurinol, Bcg vaccine live. The full list is on the Ampicillin-sulbactam page.
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