藥物交互作用
Anagrelide + Solifenacin
嚴重程度: 嚴重
Anagrelide and Solifenacin: major interaction.
最後更新
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摘要
Both drugs can prolong the QT interval, so co-use may increase the risk of ventricular arrhythmias such as torsades de pointes. Anagrelide can also cause tachycardia and palpitations.
用白話說明這項交互作用的意義
Anagrelide and Solifenacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anagrelide belongs to Cardiovascular; Solifenacin belongs to Genitourinary.
為什麼會發生
Additive QT prolongation through pharmacodynamic effects.
處置方式
Avoid if possible or obtain a baseline ECG and monitor it, keeping potassium and magnesium within normal range.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Solifenacin 的其他交互作用
Anagrelide 的其他交互作用
常見問題
Can I take Anagrelide with Solifenacin?
MediHelp rates the interaction as major. Anagrelide and Solifenacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can prolong the QT interval, so co-use may increase the risk of ventricular arrhythmias such as torsades de pointes. Anagrelide can also cause tachycardia and palpitations.
How serious is the interaction between Anagrelide and Solifenacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible or obtain a baseline ECG and monitor it, keeping potassium and magnesium within normal range.
What other medicines interact with Solifenacin?
MediHelp also lists interactions of Solifenacin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Solifenacin page.
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