藥物交互作用
Anastrozole + Ethinyl estradiol-levonorgestrel
嚴重程度: 嚴重
Anastrozole and Ethinyl estradiol-levonorgestrel: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Anastrozole lowers estrogen levels in postmenopausal breast cancer. Estrogen-containing contraceptives supply exogenous estrogen and may counteract therapy and stimulate hormone-sensitive tumor.
用白話說明這項交互作用的意義
Anastrozole and Ethinyl estradiol-levonorgestrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anastrozole belongs to Oncology; Ethinyl estradiol-levonorgestrel belongs to Endocrine.
為什麼會發生
Pharmacodynamic antagonism between exogenous estrogen and aromatase inhibition.
處置方式
Avoid estrogen-containing products during anastrozole therapy. Use a non-hormonal contraceptive if contraception is required.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Ethinyl estradiol-levonorgestrel 的其他交互作用
- Ethinyl estradiol-levonorgestrel + Fezolinetant 禁忌併用
- Ethinyl estradiol-levonorgestrel + Ombitasvir / paritaprevir / ritonavir and dasabuvir 禁忌併用
- Ethinyl estradiol-levonorgestrel + Tranexamic acid 禁忌併用
- Aminocaproic acid + Ethinyl estradiol-levonorgestrel 嚴重
- Amobarbital + Ethinyl estradiol-levonorgestrel 嚴重
- Antithrombin alfa + Ethinyl estradiol-levonorgestrel 嚴重
Anastrozole 的其他交互作用
常見問題
Can I take Anastrozole with Ethinyl estradiol-levonorgestrel?
MediHelp rates the interaction as major. Anastrozole and Ethinyl estradiol-levonorgestrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Anastrozole lowers estrogen levels in postmenopausal breast cancer. Estrogen-containing contraceptives supply exogenous estrogen and may counteract therapy and stimulate hormone-sensitive tumor.
How serious is the interaction between Anastrozole and Ethinyl estradiol-levonorgestrel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid estrogen-containing products during anastrozole therapy. Use a non-hormonal contraceptive if contraception is required.
What other medicines interact with Ethinyl estradiol-levonorgestrel?
MediHelp also lists interactions of Ethinyl estradiol-levonorgestrel with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Tranexamic acid. The full list is on the Ethinyl estradiol-levonorgestrel page.
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