藥物交互作用
Dalteparin + Prasugrel
嚴重程度: 嚴重
Dalteparin and Prasugrel: major interaction.
最後更新
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摘要
Prasugrel is a potent P2Y12 inhibitor, and combining it with a low-molecular-weight heparin increases the risk of major bleeding. This is common in acute coronary syndrome but needs careful oversight.
用白話說明這項交互作用的意義
Dalteparin and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dalteparin belongs to Cardiovascular; Prasugrel belongs to Cardiovascular.
為什麼會發生
Additive effects of platelet P2Y12 blockade and antithrombin-mediated inhibition of factor Xa and thrombin.
處置方式
Use only when clearly indicated and limit anticoagulant duration. Monitor hemoglobin, platelets and bleeding signs, and consider a gastroprotective agent.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Dalteparin 的其他交互作用
Prasugrel 的其他交互作用
常見問題
Can I take Dalteparin with Prasugrel?
MediHelp rates the interaction as major. Dalteparin and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Prasugrel is a potent P2Y12 inhibitor, and combining it with a low-molecular-weight heparin increases the risk of major bleeding. This is common in acute coronary syndrome but needs careful oversight.
How serious is the interaction between Dalteparin and Prasugrel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only when clearly indicated and limit anticoagulant duration. Monitor hemoglobin, platelets and bleeding signs, and consider a gastroprotective agent.
What other medicines interact with Dalteparin?
MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
