藥物交互作用
Argatroban + Piperacillin-tazobactam
嚴重程度: 中度
Argatroban and Piperacillin-tazobactam: moderate interaction.
最後更新
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摘要
High-dose piperacillin can impair platelet function and may add to the bleeding tendency of anticoagulants. The effect on argatroban is largely theoretical and generally small at usual doses.
用白話說明這項交互作用的意義
Argatroban and Piperacillin-tazobactam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Argatroban belongs to Cardiovascular; Piperacillin-tazobactam belongs to Anti Bacterial.
為什麼會發生
Piperacillin impairs platelet aggregation, adding to argatroban's anticoagulant effect on hemostasis.
處置方式
Monitor aPTT and watch for signs of bleeding, especially with renal impairment or high piperacillin doses.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Piperacillin-tazobactam 的其他交互作用
Argatroban 的其他交互作用
常見問題
Can I take Argatroban with Piperacillin-tazobactam?
MediHelp rates the interaction as moderate. Argatroban and Piperacillin-tazobactam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. High-dose piperacillin can impair platelet function and may add to the bleeding tendency of anticoagulants. The effect on argatroban is largely theoretical and generally small at usual doses.
How serious is the interaction between Argatroban and Piperacillin-tazobactam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor aPTT and watch for signs of bleeding, especially with renal impairment or high piperacillin doses.
What other medicines interact with Piperacillin-tazobactam?
MediHelp also lists interactions of Piperacillin-tazobactam with, for example, Vancomycin, Amikacin, Antithrombin alfa. The full list is on the Piperacillin-tazobactam page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
