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Piperacillin-tazobactam

Piperacillin-tazobactam is a medicine in the class anti bacterial. It is used for female pelvic infections.

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僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Anti Bacterial
常見劑型
注射劑, 輸注液
常見規格
4.5 g, 2.25 g, 2 g
已知交互作用
54 (嚴重: 1 · 中度: 32 · 輕微: 21)
商品名
30
國家與市場
4

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Antipseudomonal penicillin plus beta-lactamase inhibitor; inhibits biosynthesis of cell wall mucopeptide synthesis by binding to 1 or more of the penicillin-binding proteins and is effective during active-multiplication stage

成人常用劑量（仿單摘要）

Intra-abdominal Infections: 3.375 g IV q6hr (totaling 13.5 g [12 g piperacillin/1.5 g tazobactam]) for 7-10 days

僅摘錄仿單中第一行劑量說明；完整的劑量內容請見 App。

一般服用方式

Penicillin antibiotics are taken by mouth or given by injection at regular intervals for a set number of days; the course should be completed even when symptoms improve early.

確切的劑量、服用時間與療程長短，由開立處方者及產品仿單決定；登入後，MediHelp 會顯示完整的劑量內容。

懷孕與哺乳

懷孕
Safe Both drugs cross the placenta; there are insufficient data to show a risk, and penicillins have long use in pregnancy without evidence of fetal harm. No malformations in rats or mice. Safe to use when indicated.
哺乳
Safe Piperacillin passes into milk in low amounts, not expected to harm the infant; tazobactam is unstudied. LactMed: occasionally diarrhoea or thrush. Acceptable; breastfeeding can continue.

已通報的副作用

  • Headache
  • Diarrhea
  • Nausea
  • Insomnia
  • Constipation
  • Fever

禁忌症

  • Allergy to penicillins, cephalosporins, imipenem, beta-lactamase inhibitors

哪些人需要特別留意

  • Prolonged use may result in fungal or bacterial superinfection
  • Leukopenia/neutropenia associated with prolonged therapy; periodic assessment of hematopoietic function should be performed,
  • Increased frequency of fever and rash reported in patients with cystic fibrosis receiving piperacillin

Anyone who has had an allergic reaction to a penicillin or another beta-lactam antibiotic must tell the prescriber before taking one. Severe or persistent diarrhoea during or after a course needs medical advice.

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。

重要交互作用 (54)

All 54 interactions, with severity and what to do

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用，即可開啟 Piperacillin-tazobactam 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • Paediatric dosing
  • Pharmacokinetics
  • Patient counselling points
  • Food interactions
  • IV preparation and dilution
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同類別的其他藥品

常見問題

What is Piperacillin-tazobactam used for?

Piperacillin-tazobactam is a medicine in the class anti bacterial. It is used for Female pelvic infections, Intra-abdominal infections, Pneumonia, Sepsis, Skin infections.

What side effects have been reported with Piperacillin-tazobactam?

Headache, Diarrhea, Nausea, Insomnia, Constipation, Fever.

Can Piperacillin-tazobactam be taken in pregnancy or while breastfeeding?

Pregnancy: Safe. Both drugs cross the placenta; there are insufficient data to show a risk, and penicillins have long use in pregnancy without evidence of fetal harm. No malformations in rats or mice. Safe to use when indicated. Breastfeeding: Safe. Piperacillin passes into milk in low amounts, not expected to harm the infant; tazobactam is unstudied. LactMed: occasionally diarrhoea or thrush. Acceptable; breastfeeding can continue.

What does Piperacillin-tazobactam interact with?

MediHelp lists 54 known interactions for Piperacillin-tazobactam. Major: 1 · Moderate: 32 · Minor: 21. The most serious include Vancomycin, Amikacin, Antithrombin alfa.

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