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藥物交互作用

Aripiprazole + Methyldopa

嚴重程度: 中度

Aripiprazole and Methyldopa: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Aripiprazole's D2 partial agonism can blunt the effect of methyldopa. Symptom control or haemodynamic response may be lessened.

用白話說明這項交互作用的意義

Aripiprazole and Methyldopa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Aripiprazole belongs to Central Nervous System; Methyldopa belongs to Cardiovascular.

證據等級: Low

為什麼會發生

D2 partial agonism/antagonism opposes dopaminergic therapy

處置方式

Monitor therapeutic response; adjust doses if control is inadequate.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Aripiprazole 與 Methyldopa 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Aripiprazole with Methyldopa?

MediHelp rates the interaction as moderate. Aripiprazole and Methyldopa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aripiprazole's D2 partial agonism can blunt the effect of methyldopa. Symptom control or haemodynamic response may be lessened.

How serious is the interaction between Aripiprazole and Methyldopa?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor therapeutic response; adjust doses if control is inadequate.

What other medicines interact with Methyldopa?

MediHelp also lists interactions of Methyldopa with, for example, Tranylcypromine, Iobenguane i, Lofexidine. The full list is on the Methyldopa page.

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