藥物交互作用
Asciminib + Moxifloxacin
嚴重程度: 嚴重
Asciminib and Moxifloxacin: major interaction.
最後更新
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摘要
Moxifloxacin and asciminib can each prolong the QT interval, so together they raise the risk of torsades de pointes. Patients with electrolyte abnormalities or heart disease are at higher risk.
用白話說明這項交互作用的意義
Asciminib and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Asciminib belongs to Oncology; Moxifloxacin belongs to Anti Bacterial.
為什麼會發生
Additive QT interval prolongation.
處置方式
Avoid with asciminib 200 mg twice daily. At lower doses, use an alternative antibiotic if possible, otherwise monitor ECG and electrolytes.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Asciminib 的其他交互作用
Moxifloxacin 的其他交互作用
常見問題
Can I take Asciminib with Moxifloxacin?
MediHelp rates the interaction as major. Asciminib and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Moxifloxacin and asciminib can each prolong the QT interval, so together they raise the risk of torsades de pointes. Patients with electrolyte abnormalities or heart disease are at higher risk.
How serious is the interaction between Asciminib and Moxifloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid with asciminib 200 mg twice daily. At lower doses, use an alternative antibiotic if possible, otherwise monitor ECG and electrolytes.
What other medicines interact with Asciminib?
MediHelp also lists interactions of Asciminib with, for example, Clarithromycin, Dihydroergotamine, Ergotamine. The full list is on the Asciminib page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
