藥物交互作用
Atenolol-chlorthalidone + Calcium acetate
嚴重程度: 中度
Atenolol-chlorthalidone and Calcium acetate: moderate interaction.
最後更新
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摘要
Calcium salts can reduce atenolol absorption in the gut, which may lessen its effect on heart rate and blood pressure. Chlorthalidone also reduces urinary calcium excretion, so calcium load can add to hypercalcaemia risk.
用白話說明這項交互作用的意義
Atenolol-chlorthalidone and Calcium acetate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol-chlorthalidone belongs to Cardiovascular; Calcium acetate belongs to Genitourinary.
為什麼會發生
Calcium may bind atenolol or otherwise reduce its gastrointestinal absorption, and thiazides reduce renal calcium excretion.
處置方式
Separate atenolol and calcium acetate by at least 2 hours. Monitor serum calcium and blood pressure.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Atenolol-chlorthalidone 的其他交互作用
Calcium acetate 的其他交互作用
常見問題
Can I take Atenolol-chlorthalidone with Calcium acetate?
MediHelp rates the interaction as moderate. Atenolol-chlorthalidone and Calcium acetate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium salts can reduce atenolol absorption in the gut, which may lessen its effect on heart rate and blood pressure. Chlorthalidone also reduces urinary calcium excretion, so calcium load can add to hypercalcaemia risk.
How serious is the interaction between Atenolol-chlorthalidone and Calcium acetate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate atenolol and calcium acetate by at least 2 hours. Monitor serum calcium and blood pressure.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
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