藥物交互作用
Calcium acetate + Captopril-hydrochlorothiazide
嚴重程度: 中度
Calcium acetate and Captopril-hydrochlorothiazide: moderate interaction.
最後更新
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摘要
Thiazides reduce urinary calcium excretion, so supplemental calcium can raise serum calcium. High calcium intake with thiazides can lead to hypercalcemia and, with absorbable alkali, milk-alkali syndrome.
用白話說明這項交互作用的意義
Calcium acetate and Captopril-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium acetate belongs to Genitourinary; Captopril-hydrochlorothiazide belongs to Cardiovascular.
為什麼會發生
Thiazides enhance distal tubular calcium reabsorption, reducing renal calcium clearance.
處置方式
Monitor serum calcium periodically and reduce the calcium dose if hypercalcemia develops, especially in renal impairment.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Captopril-hydrochlorothiazide 的其他交互作用
Calcium acetate 的其他交互作用
常見問題
Can I take Calcium acetate with Captopril-hydrochlorothiazide?
MediHelp rates the interaction as moderate. Calcium acetate and Captopril-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiazides reduce urinary calcium excretion, so supplemental calcium can raise serum calcium. High calcium intake with thiazides can lead to hypercalcemia and, with absorbable alkali, milk-alkali syndrome.
How serious is the interaction between Calcium acetate and Captopril-hydrochlorothiazide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium periodically and reduce the calcium dose if hypercalcemia develops, especially in renal impairment.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
