藥物交互作用
Azilsartan-chlorthalidone + Calcium acetate
嚴重程度: 中度
Azilsartan-chlorthalidone and Calcium acetate: moderate interaction.
最後更新
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摘要
Chlorthalidone reduces urinary calcium excretion, so calcium salts may raise serum calcium. Hypercalcemia is more likely with high doses, renal impairment or vitamin D therapy.
用白話說明這項交互作用的意義
Azilsartan-chlorthalidone and Calcium acetate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azilsartan-chlorthalidone belongs to Cardiovascular; Calcium acetate belongs to Genitourinary.
為什麼會發生
Thiazide-type diuretics increase distal tubular calcium reabsorption, reducing calcium excretion.
處置方式
Monitor serum calcium periodically and reduce the calcium dose if hypercalcemia develops.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Azilsartan-chlorthalidone 的其他交互作用
Calcium acetate 的其他交互作用
常見問題
Can I take Azilsartan-chlorthalidone with Calcium acetate?
MediHelp rates the interaction as moderate. Azilsartan-chlorthalidone and Calcium acetate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chlorthalidone reduces urinary calcium excretion, so calcium salts may raise serum calcium. Hypercalcemia is more likely with high doses, renal impairment or vitamin D therapy.
How serious is the interaction between Azilsartan-chlorthalidone and Calcium acetate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium periodically and reduce the calcium dose if hypercalcemia develops.
What other medicines interact with Azilsartan-chlorthalidone?
MediHelp also lists interactions of Azilsartan-chlorthalidone with, for example, Aliskiren, Sparsentan, Aceclofenac. The full list is on the Azilsartan-chlorthalidone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
