藥物交互作用
Atropine + Trospium
嚴重程度: 中度
Atropine and Trospium: moderate interaction.
最後更新
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摘要
Atropine is a systemic antimuscarinic and adds to trospium's effects. This can cause dry mouth, constipation, urinary retention, tachycardia, blurred vision and confusion.
用白話說明這項交互作用的意義
Atropine and Trospium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atropine belongs to Miscellaneous; Trospium belongs to Genitourinary.
為什麼會發生
Additive antimuscarinic pharmacodynamic effects.
處置方式
Monitor for anticholinergic toxicity such as urinary retention and tachycardia. Reduce doses or avoid the combination in patients at risk, such as the elderly.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Trospium 的其他交互作用
Atropine 的其他交互作用
常見問題
Can I take Atropine with Trospium?
MediHelp rates the interaction as moderate. Atropine and Trospium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atropine is a systemic antimuscarinic and adds to trospium's effects. This can cause dry mouth, constipation, urinary retention, tachycardia, blurred vision and confusion.
How serious is the interaction between Atropine and Trospium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic toxicity such as urinary retention and tachycardia. Reduce doses or avoid the combination in patients at risk, such as the elderly.
What other medicines interact with Trospium?
MediHelp also lists interactions of Trospium with, for example, Clozapine, Pramlintide, Thioridazine. The full list is on the Trospium page.
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