藥物交互作用
Bacitracin + Valacyclovir
嚴重程度: 中度
Bacitracin and Valacyclovir: moderate interaction.
最後更新
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摘要
Systemic bacitracin is nephrotoxic, and with valacyclovir, whose active form acyclovir is renally cleared, kidney injury risk increases. Topical bacitracin has negligible systemic exposure.
用白話說明這項交互作用的意義
Bacitracin and Valacyclovir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bacitracin belongs to Miscellaneous; Valacyclovir belongs to Anti Virals.
為什麼會發生
Additive nephrotoxicity and reduced renal clearance of acyclovir.
處置方式
Avoid systemic bacitracin with valacyclovir where possible. Otherwise maintain hydration, monitor creatinine and adjust valacyclovir dose for renal function.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Valacyclovir 的其他交互作用
Bacitracin 的其他交互作用
常見問題
Can I take Bacitracin with Valacyclovir?
MediHelp rates the interaction as moderate. Bacitracin and Valacyclovir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic bacitracin is nephrotoxic, and with valacyclovir, whose active form acyclovir is renally cleared, kidney injury risk increases. Topical bacitracin has negligible systemic exposure.
How serious is the interaction between Bacitracin and Valacyclovir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic bacitracin with valacyclovir where possible. Otherwise maintain hydration, monitor creatinine and adjust valacyclovir dose for renal function.
What other medicines interact with Valacyclovir?
MediHelp also lists interactions of Valacyclovir with, for example, Talimogene laherparepvec, Cilastatin-imipenem, Elvitegravir / cobicistat / emtricitabine / tenofovir df. The full list is on the Valacyclovir page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
