藥物交互作用
Bevacizumab + Efgartigimod / hyaluronidase sc
嚴重程度: 中度
Bevacizumab and Efgartigimod / hyaluronidase sc: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Subcutaneous efgartigimod blocks the neonatal Fc receptor, which may speed clearance of IgG antibodies such as bevacizumab and lower their exposure.
用白話說明這項交互作用的意義
Bevacizumab and Efgartigimod / hyaluronidase sc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
FcRn blockade reduces IgG recycling and shortens the half-life of IgG monoclonal antibodies.
處置方式
Monitor for reduced bevacizumab response; consider alternatives to either drug if long-term combination is needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Bevacizumab 的其他交互作用
常見問題
Can I take Bevacizumab with Efgartigimod / hyaluronidase sc?
MediHelp rates the interaction as moderate. Bevacizumab and Efgartigimod / hyaluronidase sc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Subcutaneous efgartigimod blocks the neonatal Fc receptor, which may speed clearance of IgG antibodies such as bevacizumab and lower their exposure.
How serious is the interaction between Bevacizumab and Efgartigimod / hyaluronidase sc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced bevacizumab response; consider alternatives to either drug if long-term combination is needed.
What other medicines interact with Bevacizumab?
MediHelp also lists interactions of Bevacizumab with, for example, Sunitinib, Daunorubicin, Dengue vaccine. The full list is on the Bevacizumab page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
