藥物交互作用
Bevacizumab + Daunorubicin
嚴重程度: 中度
Bevacizumab and Daunorubicin: moderate interaction.
最後更新
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摘要
Daunorubicin is cardiotoxic, and bevacizumab can cause hypertension and, less commonly, heart failure. Combined use may increase cardiac risk, particularly in patients with prior anthracycline exposure.
用白話說明這項交互作用的意義
Bevacizumab and Daunorubicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bevacizumab belongs to Oncology; Daunorubicin belongs to Oncology.
為什麼會發生
Additive cardiotoxicity from anthracycline myocardial injury and VEGF inhibition-related hypertension and cardiac stress.
處置方式
Assess left ventricular function before and during treatment and monitor blood pressure. Treat hypertension promptly and stop therapy if heart failure develops.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Daunorubicin 的其他交互作用
Bevacizumab 的其他交互作用
常見問題
Can I take Bevacizumab with Daunorubicin?
MediHelp rates the interaction as moderate. Bevacizumab and Daunorubicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Daunorubicin is cardiotoxic, and bevacizumab can cause hypertension and, less commonly, heart failure. Combined use may increase cardiac risk, particularly in patients with prior anthracycline exposure.
How serious is the interaction between Bevacizumab and Daunorubicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess left ventricular function before and during treatment and monitor blood pressure. Treat hypertension promptly and stop therapy if heart failure develops.
What other medicines interact with Daunorubicin?
MediHelp also lists interactions of Daunorubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cyclosporine. The full list is on the Daunorubicin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
