藥物交互作用
Bisoprolol + Cocaine
嚴重程度: 嚴重
Bisoprolol and Cocaine: major interaction.
最後更新
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摘要
Cocaine stimulates alpha-adrenergic receptors, and beta-blockade may leave this unopposed, increasing the potential for vasoconstriction, hypertension and coronary ischemia. This concern is most relevant with systemic or illicit cocaine, while topical medical use has low exposure.
用白話說明這項交互作用的意義
Bisoprolol and Cocaine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bisoprolol belongs to Cardiovascular; Cocaine belongs to Central Nervous System.
為什麼會發生
Beta-blockade leaves cocaine-induced alpha-adrenergic vasoconstriction unopposed.
處置方式
Avoid cocaine use in patients taking beta-blockers. If exposure occurs, treat hypertension and ischemia with vasodilators rather than additional beta-blockers.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Bisoprolol 的其他交互作用
Cocaine 的其他交互作用
常見問題
Can I take Bisoprolol with Cocaine?
MediHelp rates the interaction as major. Bisoprolol and Cocaine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cocaine stimulates alpha-adrenergic receptors, and beta-blockade may leave this unopposed, increasing the potential for vasoconstriction, hypertension and coronary ischemia. This concern is most relevant with systemic or illicit cocaine, while topical medical use has low exposure.
How serious is the interaction between Bisoprolol and Cocaine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid cocaine use in patients taking beta-blockers. If exposure occurs, treat hypertension and ischemia with vasodilators rather than additional beta-blockers.
What other medicines interact with Bisoprolol?
MediHelp also lists interactions of Bisoprolol with, for example, Aldesleukin, Amifostine, Amiodarone. The full list is on the Bisoprolol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
