藥品參考
Cocaine
Cocaine is a medicine in the class central nervous system. It is used for local anesthetic.
- 藥物類別: Central Nervous System
- 用途: local anesthetic
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Central Nervous System
- 常見劑型
- 溶液
- 常見規格
- 40 mg/ml
- 已知交互作用
- 64 (禁忌併用: 3 · 嚴重: 19 · 中度: 33 · 輕微: 9)
- 商品名
- 2
- 國家與市場
- 1
用途
作用方式
Ester-type local anesthetic that reversibly blocks sodium channels, preventing the transient rise in sodium conductance needed for an action potential, so nerve fibers cannot conduct.
成人常用劑量（仿單摘要）
Local anesthesia of nasal mucous membranes for diagnostic procedures and surgery: two soaked pledgets (40 mg each) in each nasal cavity, intranasal, once; total 160 mg. Do not exceed 160 mg or 3 mg/kg per procedure.
懷孕與哺乳
- 懷孕
- Unsafe May cause fetal harm. Animal studies showed malformations and increased pup mortality; no human data on intranasal use.
- 哺乳
- Unsafe Cocaine is present in breast milk; no level of exposure is considered safe for a breastfed infant. Avoid breastfeeding for 48 hours after treatment.
已通報的副作用
- Headache
- Epistaxis
黑框警語
- CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence.
禁忌症
- Known hypersensitivity to cocaine hydrochloride, other ester-based anesthetics, or any other component of the product.
哪些人需要特別留意
- May lower the convulsive threshold; monitor for seizures.
- Increases blood pressure and heart rate; monitor vital signs, heart rate and rhythm. Avoid in recent or active uncontrolled hypertension, unstable angina, MI, coronary artery disease, or CHF.
- Cocaine may be detected in plasma for up to one week, and cocaine and its metabolites in urine for longer than one week, which may affect toxicology screening.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (64)
- Cocaine + Isocarboxazid Contraindicated
- Cocaine + Phenelzine Contraindicated
- Cocaine + Procarbazine Contraindicated
- Amitriptyline + Cocaine Major
- Bisoprolol + Cocaine Major
- Citalopram + Cocaine Major
- Clomipramine + Cocaine Major
- Cocaine + Desipramine Major
- Cocaine + Dextroamphetamine Major
- Cocaine + Duloxetine Major
同類別的其他藥品
常見問題
What is Cocaine used for?
Cocaine is a medicine in the class central nervous system. It is used for Local anesthetic.
What side effects have been reported with Cocaine?
Headache, Epistaxis. Serious warning: CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence.
Can Cocaine be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. May cause fetal harm. Animal studies showed malformations and increased pup mortality; no human data on intranasal use. Breastfeeding: Unsafe. Cocaine is present in breast milk; no level of exposure is considered safe for a breastfed infant. Avoid breastfeeding for 48 hours after treatment.
What does Cocaine interact with?
MediHelp lists 64 known interactions for Cocaine. Contraindicated: 3 · Major: 19 · Moderate: 33 · Minor: 9. The most serious include Isocarboxazid, Phenelzine, Procarbazine.
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