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Butabarbital + Melatonin

嚴重程度: 中度

Butabarbital and Melatonin: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Butabarbital is a barbiturate sedative-hypnotic, and melatonin adds a mild sedative effect. Together they may increase drowsiness and next-day impairment.

用白話說明這項交互作用的意義

Butabarbital and Melatonin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

證據等級: Low

為什麼會發生

Additive CNS depression via GABA-A potentiation by the barbiturate and melatonin receptor-mediated sedation.

處置方式

Avoid combining for sleep where possible; if used together, monitor for excessive sedation and advise against driving or operating machinery.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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解鎖完整頁面

建立帳號並開始 Pro+ 試用，即可解鎖 Butabarbital 與 Melatonin 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription
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常見問題

Can I take Butabarbital with Melatonin?

MediHelp rates the interaction as moderate. Butabarbital and Melatonin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Butabarbital is a barbiturate sedative-hypnotic, and melatonin adds a mild sedative effect. Together they may increase drowsiness and next-day impairment.

How serious is the interaction between Butabarbital and Melatonin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining for sleep where possible; if used together, monitor for excessive sedation and advise against driving or operating machinery.

What other medicines interact with Melatonin?

MediHelp also lists interactions of Melatonin with, for example, Fluvoxamine, Alfentanil, Belladonna and opium. The full list is on the Melatonin page.

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