藥物交互作用
Butalbital + Melatonin
嚴重程度: 中度
Butalbital and Melatonin: moderate interaction.
最後更新
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摘要
Butalbital is a barbiturate that causes sedation, and melatonin may add to drowsiness. Impaired alertness and psychomotor performance are possible.
用白話說明這項交互作用的意義
Butalbital and Melatonin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive CNS depression from barbiturate GABA-A potentiation and melatonin-mediated sedation.
處置方式
Counsel patients about additive drowsiness and avoid driving until response is known; reduce or stop melatonin if excessive sedation occurs.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Melatonin 的其他交互作用
常見問題
Can I take Butalbital with Melatonin?
MediHelp rates the interaction as moderate. Butalbital and Melatonin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Butalbital is a barbiturate that causes sedation, and melatonin may add to drowsiness. Impaired alertness and psychomotor performance are possible.
How serious is the interaction between Butalbital and Melatonin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about additive drowsiness and avoid driving until response is known; reduce or stop melatonin if excessive sedation occurs.
What other medicines interact with Melatonin?
MediHelp also lists interactions of Melatonin with, for example, Fluvoxamine, Alfentanil, Belladonna and opium. The full list is on the Melatonin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。